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Molecular Biology Physiology & Disease

Intismeran-Keytruda: An mRNA vaccine combined with immunotherapy against melanoma

Melanoma is one of the most common and life-threatening types of cancer, affecting thousands of people every year. In 2024 alone, there were more than 58000 deaths as a result of melanoma. It is estimated that the number of new melanoma cases will increase further in the upcoming years, especially in younger age groups. Melanoma: […]

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Physiology & Disease

SGOT and SGPT levels as disease biomarkers

You just received the results of a routine blood test. As you review the results and compare them with the reference values, you notice a slight elevation of SGPT levels. A quick internet search reveals something about possible liver damage, and you start to worry. But what could this elevation really mean? What information do […]

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Microbiology Physiology & Disease

How to identify Gram-positive cocci

One day, you woke up with a mild irritation on your arm. The skin was red and itchy. You paid no attention. But the next day, you noticed more bumps filled with pus. It looked concerning, so you decided to check it out with your dermatologist. The doctor collected a sample from the wound and […]

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Drugs and Medications

Adverse Drug Events And Reactions

When scientists test a new drug in clinical trials, their purpose is to gather data that will help them assess if it is safe and effective. However, no matter their efforts, all drugs have side effects, whether they are still under investigation in clinical trials or have been authorized for use. That means that when […]

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Drugs and Medications

Basics of Clinical Trials

When scientists work on a new project, for example, the discovery of a new drug, it may take decades to reach the market. It often requires years of research in the lab, computer simulations, or tests on laboratory animals. Preclinical results from animal testing help scientists identify if the candidate drug is toxic or safe […]

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Microbiology Physiology & Disease

Toxoplasmosis and Pregnancy

Did you know that a parasitic infection can put a pregnancy at risk of serious complications? Toxoplasmosis, caused by Toxoplasma gondii, a little parasite that uses cats as its definitive host, can sometimes disrupt normal fetal development. But what factors affect the chance of transmission from the mother to the fetus, how can toxoplasmosis be […]

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Animals Evolutionary Biology

Extinction and De-extinction of the Dodo

The Dodo, a flightless bird that looked like a huge pigeon and lived in Mauritius, has become a symbol of extinction. Although many species have become extinct in the history of life on earth, the Dodo is still often talked about, probably because of the anthropogenic causes of its extinction. Historic descriptions and data collection […]

Categories
Molecular Biology New Technologies Physiology & Disease

Casgevy: The first authorized CRISPR-based gene editing therapy

It’s been almost four years since professors Jennifer Doudna and Emmanuelle Charpentier received the Nobel Prize in Chemistry for discovering the now well-known genome editing CRISPR/Cas9 system. Since then, researchers have tried to utilize this tool to induce targeted alterations in DNA to repair faulty genes or change specific nucleotide sequences in the fight against […]

Categories
Animals Evolutionary Biology

Tardigrades and their fascinating genome

Tardigrades, also known as little water bears because of their morphology, are strange little creatures, popular among scientists trying to decipher the unique features that enable them to survive under extreme conditions. Many articles have been published regarding their genetic makeup in the hopes of using this information to treat disease or fight the consequences […]

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Physiology & Disease

The science behind twins

Do you have any family members or friends that are twins? If so, can you tell them apart, or do they look like two peas in a pod? Either way, it is fascinating to think that a woman can deliver more than one baby at a time. These cases are called multiple births. Twins are […]