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Molecular Biology Physiology & Disease

Intismeran-Keytruda: An mRNA vaccine combined with immunotherapy against melanoma

Melanoma is one of the most common and life-threatening types of cancer, affecting thousands of people every year. In 2024 alone, there were more than 58000 deaths as a result of melanoma. It is estimated that the number of new melanoma cases will increase further in the upcoming years, especially in younger age groups. Melanoma: […]

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Physiology & Disease

SGOT and SGPT levels as disease biomarkers

You just received the results of a routine blood test. As you review the results and compare them with the reference values, you notice a slight elevation of SGPT levels. A quick internet search reveals something about possible liver damage, and you start to worry. But what could this elevation really mean? What information do […]

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Microbiology Physiology & Disease

How to identify Gram-positive cocci

One day, you woke up with a mild irritation on your arm. The skin was red and itchy. You paid no attention. But the next day, you noticed more bumps filled with pus. It looked concerning, so you decided to check it out with your dermatologist. The doctor collected a sample from the wound and […]

Categories
Microbiology Physiology & Disease

Toxoplasmosis and Pregnancy

Did you know that a parasitic infection can put a pregnancy at risk of serious complications? Toxoplasmosis, caused by Toxoplasma gondii, a little parasite that uses cats as its definitive host, can sometimes disrupt normal fetal development. But what factors affect the chance of transmission from the mother to the fetus, how can toxoplasmosis be […]

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Molecular Biology New Technologies Physiology & Disease

Casgevy: The first authorized CRISPR-based gene editing therapy

It’s been almost four years since professors Jennifer Doudna and Emmanuelle Charpentier received the Nobel Prize in Chemistry for discovering the now well-known genome editing CRISPR/Cas9 system. Since then, researchers have tried to utilize this tool to induce targeted alterations in DNA to repair faulty genes or change specific nucleotide sequences in the fight against […]

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Physiology & Disease

The science behind twins

Do you have any family members or friends that are twins? If so, can you tell them apart, or do they look like two peas in a pod? Either way, it is fascinating to think that a woman can deliver more than one baby at a time. These cases are called multiple births. Twins are […]

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Microbiology Physiology & Disease

A glimpse into the immune system

One morning, you hang out with a friend who is coughing and sneezing. You spend some time together, you wish them well, and go home. A few days later, you wake up with a sore throat, a runny nose, and maybe a fever. What happened? You quickly remember your friend. You probably caught a virus. […]

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Physiology & Disease

Sickle cell anemia and malaria

It is already known that mutations (changes in the DNA sequence) often alter the genetic information resulting in changes in the functions of cells and hence of organisms, leading to disease. So, one would expect that if a mutation is linked to a disease, it would only cause disadvantages to an individual or their offsprings. […]

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Physiology & Disease

Hemolytic disease of the newborn

Hemolytic Disease of the Newborn (HDN) is a type of anemia that occurs when the mother’s immune system attacks and destroys the fetal red blood cells as a result of an incompatibility between the mother’s and the baby’s blood group. Another term used for this condition is Erythroblastosis fetalis, but we will discuss the reason […]

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Physiology & Disease

What is your blood type?

“I am type B. I can’t donate blood for your surgery. We need to find another donor.” Have you ever wondered what it is that determines your blood type or why it’s so important for doctors to know their patient’s blood type before transfusion? Let’s learn as much information as we can. The International Society […]