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Molecular Biology Physiology & Disease

Intismeran-Keytruda: An mRNA vaccine combined with immunotherapy against melanoma

Melanoma is one of the most common and life-threatening types of cancer, affecting thousands of people every year. In 2024 alone, there were more than 58000 deaths as a result of melanoma. It is estimated that the number of new melanoma cases will increase further in the upcoming years, especially in younger age groups. Melanoma: […]

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Molecular Biology New Technologies Physiology & Disease

Casgevy: The first authorized CRISPR-based gene editing therapy

It’s been almost four years since professors Jennifer Doudna and Emmanuelle Charpentier received the Nobel Prize in Chemistry for discovering the now well-known genome editing CRISPR/Cas9 system. Since then, researchers have tried to utilize this tool to induce targeted alterations in DNA to repair faulty genes or change specific nucleotide sequences in the fight against […]

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Molecular Biology

Unraveling the double helix

We learned in a previous post that in 1952, after a lot of experiments, DNA was accepted by the scientific community as the genetic material of the cells. However, something was still missing, and that was its structure. For many years prior, scientists were conducting experiments, each one unraveling some features of DNA that proved […]

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Molecular Biology

Classic experiments: DNA as the genetic material

In a previous post, we learned that DNA is the genetic material of the cells, and one of its most important functions is that it contains genes that carry the information for the determination of the hereditary characteristics. However, scientists were not always aware that DNA was the genetic material. In fact, for the first half […]

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Molecular Biology

The genetic material

DNA or Deoxyribonucleic acid is the genetic material of all the cells and most viruses, with the exception of some viruses that use another type of nucleic acid, called RNA or Ribonucleic acid. As we will see in the following posts, DNA presents some characteristics that make it the ideal molecule to carry out the […]

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Molecular Biology

Macromolecules

We have already talked about how eukaryotic and prokaryotic organisms organize their cells in order to carry out their functions in efficient ways. But how are the different cellular parts (or organelles in eukaryotes) formed and how do they carry out their functions? The answer is that everything inside a cell is the result of […]