Categories
Molecular Biology New Technologies Physiology & Disease

Casgevy: The first authorized CRISPR-based gene editing therapy

It’s been almost four years since professors Jennifer Doudna and Emmanuelle Charpentier received the Nobel Prize in Chemistry for discovering the now well-known genome editing CRISPR/Cas9 system. Since then, researchers have tried to utilize this tool to induce targeted alterations in DNA to repair faulty genes or change specific nucleotide sequences in the fight against […]

Categories
Physiology & Disease

Sickle cell anemia and malaria

It is already known that mutations (changes in the DNA sequence) often alter the genetic information resulting in changes in the functions of cells and hence of organisms, leading to disease. So, one would expect that if a mutation is linked to a disease, it would only cause disadvantages to an individual or their offsprings. […]

Categories
Physiology & Disease

Hemolytic disease of the newborn

Hemolytic Disease of the Newborn (HDN) is a type of anemia that occurs when the mother’s immune system attacks and destroys the fetal red blood cells as a result of an incompatibility between the mother’s and the baby’s blood group. Another term used for this condition is Erythroblastosis fetalis, but we will discuss the reason […]